Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues
Published in Nature Biotechnology, 2022
Recommended citation: Gabbutt, C., Schenck, R.O., Weisenberger, D.J. et al. (2022). "Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues." Nat Biotechnol. 40, 720-730. https://doi.org/10.1038/s41587-021-01109-w
This study presents fluctuating methylation clocks (FMCs) as a novel lineage tracing marker and demonstrates how they can be employed to quantitively infer the clonal dynamics of healthy tissue.